. Author manuscript; available in PMC: 2017 Apr 1.

Published in final edited form as: Hepatology. 2016 Jan 22;63(4):1170–1183. doi: 10.1002/hep.28390

Table 5.

Cumulative probability of mortality (unadjusted) over 23 years and age-adjusted hazard ratios for mortality by GGT decile (N=11,264), United States, 1988-2011

Mortality outcome GGT decile^*	No. of deaths	Unadjusted cumulative mortality^†	Age-adjusted
Mortality outcome GGT decile^*	No. of deaths	Unadjusted cumulative mortality^†	HR^‡	95% CI	p-value
All-cause
1-9	2,915	32.5	1.0
10	522	40.5	1.66	1.46 – 1.88	<0.001
Cardiovascular disease
1-9	1,229	14.6	1.0
10	196	17.2	1.51	1.27 – 1.80	<0.001
Cancer
1-9	743	9.4	1.0
10	135	13.9	1.54	1.12 – 2.11	0.008
Diabetes
1-9	336	4.3	1.0
10	84	9.1	2.75	2.08 – 3.63	<0.001
Liver disease
1-9	40	0.55	1.0
10	40	3.5	10.75	5.26 – 21.96	<0.001

GGT, gamma glutamyltransferase; HR, hazard ratio; CI, confidence interval.

N=9,804 in deciles 1-9 and 1,460 in decile 10. Cut-point was 58 IU/L for men and 40 IU/L for women.

^†

Estimated using Kaplan-Meier analysis.

^‡

Estimated using Cox proportional hazards regression analysis.