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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Adv Healthc Mater. 2016 Jan 28;5(6):676–687. doi: 10.1002/adhm.201500758

Figure 7.

Figure 7

Collagen thickness at inter-pillar distances bordering grooved or non-grooved features used to determine oriented tissue formation at 6 weeks in vivo. (a) Masson's Trichrome stining of samples indicates increased collagen orientation perpendicular to dentin (D) chip at the pillar boundary in the presence of grooves (scale bar = 100um). (b) Mean thickness (um) of oriented collagen bundles in vivo at non-grooved (0W, 0D) and grooved (15–60um wide, 10–30um deep) pillar borders at 6 weeks based on Masson's Trichrome staining. (Error bars: ± SD; ** p<0.01; *** p<0.001, **** p<0.0001; n=5).