Table 1.
Number of Cronkhite–Canada syndrome patients associated with gastric and colorectal cancer or adenoma
| Cancer | Adenoma | |||||||
|---|---|---|---|---|---|---|---|---|
| Gastric | Colon | Gastroduodenal | Colon | |||||
| Early | Advanced | Total | Early | Advanced | Total | |||
| Associated patients | ||||||||
| At initial presentation | 7 (3.3 %) | 6 (2.9 %) | 13 (6.2 %) | 11 (5.3 %) | 15 (7.1 %) | 26 (12.4 %) | 4 (1.9 %) | 36 (17.1 %) |
| During observation | 2 (1.0 %) | 4 (1.9 %) | 6 (2.9 %) | 10 (4.8 %) | 5 (2.4 %) | 15 (7.1 %) | 3 (1.4 %) | 29 (13.8 %) |
| Observation period (years) | 10 ± 7.1 | 11.7 ± 7.0 | 11.0 ± 6.2 | 8.8 ± 4.6 | 10.2 ± 8.2 | 9.2 ± 5.9 | 7.7 ± 7.4 | 6.4 ± 4.8 |
| Total | 9 (4.3 %) | 10 (4.8 %) | 19 (9.1 %) | 21 (10.1 %) | 20 (9.5 %) | 41 (19.5 %) | 7 (3.3 %) | 65 (31.0 %) |
| Therapeutic outcome | ||||||||
| Endoscopic resection | 6 | 16 | 3 | 35 | ||||
| Surgery | 9 | 19 | 3 | 2 | ||||
| Death | 3 | 3 | 3 | 1 | ||||
Total of 210 patients. Adenomas bearing carcinomatous foci (n = 7), and adenomas that evolved into carcinoma (n = 28) were regarded as cancer. Three patients had both gastric and colon cancers, which were counted individually. All early colon cancers were found close to the adenoma.