Skip to main content
. 2016 Jan 5;110(1):7–13. doi: 10.1016/j.bpj.2015.11.025

Figure 4.

Figure 4

hCTR1 is internalized in the presence of elevated medium Cu. Live-cell imaging of HEK 293 cells expressing CLIP-labeled hCTR1 (red) in the presence or absence of 50 μM Cu. In the absence of Cu hCTR1 is seen predominantly at the plasma membrane. In the presence of Cu, much of the hCTR1 is internalized. via endocytosis.