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. 2016 Jan 5;110(1):218–233. doi: 10.1016/j.bpj.2015.10.045

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© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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The accuracy of our model. (A) The ratio p₀/p_0,exact as N_R is varied between 1 and 20,000, for different receptor-ligand affinities. The other model parameters are N_L = 150, V_eff = 2.7 × 10³ mM⁻¹. (B) The ratio p₀/p_0,exact as the concentration of an inhibitor of the ligand is varied. The parameters N_L and V_eff have the same values as in (A), and N_R = 2000.