Table 2.
The dissociation constants, KD, of HA-SA binding for various viral strains and SA
| Viral Strain | SA | KD (mM) (MST) | KD (mM) (Refitted) |
|---|---|---|---|
| X-31 | α2,6-SLN | 2.1 ± 0.3 | 1.85 ± 0.04 |
| X-31 | α2,3-SLN | 3.2 ± 0.6 | 3.88 ± 0.07 |
| HAM | α2,6-SLN | 5.9 ± 0.7 | 5.4 ± 0.2 |
| HAM | α2,3-SLN | 2.9 ± 0.3 | 3.44 ± 0.08 |
| wt H5 | α2,6-SLN | 17 ± 3 | 34 ± 4 |
| wt H5 | α2,3-SLN | 1.1 ± 0.2 | 1.20 ± 0.03 |
| wt H5 | α2,6-SL | 21 ± 6 | 37 ± 6 |
The last column lists the KD values estimated by refitting them to the virus adhesion isotherms, using the K0 and Veff parameters shown in Table 1.