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. 2016 Mar 28;22(12):3372–3380. doi: 10.3748/wjg.v22.i12.3372

Table 2.

Distribution of OGG1 and APE1 polymorphisms between cases and controls n (%)

Genotype Cases Controls OR (95%CI)1 P value
OGG1 Ser326Cys
Ser/Ser 93 (13.0) 125 (17.1) 1.00 (ref)
Ser/Cys 363 (50.8) 324 (44.4) 1.51 (1.11-2.05) 0.009
Cys/Cys 258 (36.1) 281 (38.5) 1.23 (0.90-1.69) 0.198
Ser/Cys + Cys/Cys 621 (87.0) 605 (82.9) 1.38 (1.03-1.85) 0.030
OGG1 11657A/G
A/A 648 (91.9) 654 (90.1) 1.00 (ref)
A/G 55 (7.8) 72 (9.9) 0.77 (0.53-1.12) 0.168
G/G 2 (0.3) 0 (0.0) -
A/G + G/G 57 (8.1) 72 (9.9) 0.80 (0.56-1.15) 0.230
APE1 Asp148Glu
Asp/Asp 236 (33.0) 249 (34.3) 1.00 (ref)
Asp/Glu 349 (48.8) 361 (49.7) 1.02 (0.81-1.29) 0.864
Glu/Glu 130 (18.2) 117 (16.1) 1.17 (0.86-1.60) 0.308
Asp/Glu + Glu/Glu 479 (67.0) 478 (65.8) 1.06 (0.85-1.32) 0.615
APE1 T-656G
T/T 217 (30.1) 211 (28.9) 1.00 (ref)
T/G 368 (51.0) 380 (52.0) 0.94 (0.74-1.20) 0.630
G/G 136 (18.9) 140 (19.2) 0.95 (0.70-1.28) 0.731
T/G + G/G 504 (69.9) 520 (71.1) 0.95 (0.75-1.18) 0.621
1

ORs and 95%CIs were estimated from unconditional logistic regressions after controlling for age and sex.