Table 2.
Distribution of OGG1 and APE1 polymorphisms between cases and controls n (%)
| Genotype | Cases | Controls | OR (95%CI)1 | P value |
| OGG1 Ser326Cys | ||||
| Ser/Ser | 93 (13.0) | 125 (17.1) | 1.00 (ref) | |
| Ser/Cys | 363 (50.8) | 324 (44.4) | 1.51 (1.11-2.05) | 0.009 |
| Cys/Cys | 258 (36.1) | 281 (38.5) | 1.23 (0.90-1.69) | 0.198 |
| Ser/Cys + Cys/Cys | 621 (87.0) | 605 (82.9) | 1.38 (1.03-1.85) | 0.030 |
| OGG1 11657A/G | ||||
| A/A | 648 (91.9) | 654 (90.1) | 1.00 (ref) | |
| A/G | 55 (7.8) | 72 (9.9) | 0.77 (0.53-1.12) | 0.168 |
| G/G | 2 (0.3) | 0 (0.0) | - | |
| A/G + G/G | 57 (8.1) | 72 (9.9) | 0.80 (0.56-1.15) | 0.230 |
| APE1 Asp148Glu | ||||
| Asp/Asp | 236 (33.0) | 249 (34.3) | 1.00 (ref) | |
| Asp/Glu | 349 (48.8) | 361 (49.7) | 1.02 (0.81-1.29) | 0.864 |
| Glu/Glu | 130 (18.2) | 117 (16.1) | 1.17 (0.86-1.60) | 0.308 |
| Asp/Glu + Glu/Glu | 479 (67.0) | 478 (65.8) | 1.06 (0.85-1.32) | 0.615 |
| APE1 T-656G | ||||
| T/T | 217 (30.1) | 211 (28.9) | 1.00 (ref) | |
| T/G | 368 (51.0) | 380 (52.0) | 0.94 (0.74-1.20) | 0.630 |
| G/G | 136 (18.9) | 140 (19.2) | 0.95 (0.70-1.28) | 0.731 |
| T/G + G/G | 504 (69.9) | 520 (71.1) | 0.95 (0.75-1.18) | 0.621 |
1
ORs and 95%CIs were estimated from unconditional logistic regressions after controlling for age and sex.