. 2016 Mar 28;22(12):3404–3411. doi: 10.3748/wjg.v22.i12.3404

Table 1.

Classification system for intrahepatic hepatitis B core antigen and hepatitis B surface antigen

	HBcAg	HBsAg
Distribution
Diffuse	Contiguous without skip zones	Contiguous without skip zones
Diffuse	Either in clusters or single cells	Either in clusters or single cells

Patchy	< 50% area with skip zones	< 50% area with skip zones
Patchy	Either in clusters or single cells	Either in clusters or single cells

Rare	Occasional area of entire field	Occasional area of entire field
Rare	Either in clustersor single cells	Either in clustersor single cells

Pattern	-Nuclear	-Membranous
Pattern	-Cytoplasmic	-Cytoplasmic

HBcAg: Hepatitis B core antigen; HBsAg: Hepatitis B surface antigen.