Table 1. IC₅₀ values of multiple drugs in HCC cells treated with doxorubicin (0.2 μg/mL) (Pre-Dox), hypoxia (1% O₂), ionizing radiation (10 Gy) (Pre-IR), compared with control groups (normality) (n = 6).

Cell lines	Drugs	Stimuli
		Normality	Hypoxia	Pre-Dox	Pre-IR
	Doxorubicin (μg/mL)	0.2026	1.062*	2.900*	1.130*
Huh7	5-Fluorouracil (mg/mL)	0.03799	0.2278*	3.106*	0.1739*
	Cisplatin (μg/mL)	2.831	5.841*	11.34*	5.054*
	Doxorubicin (μg/mL)	0.2776	0.5824*	1.311*	0.7392*
HepG2	5-Fluorouracil (mg/mL)	0.02016	0.05581*	1.282*	0.06292*
	Cisplatin (μg/mL)	3.288	6.630*	13.11*	5.937*

Statistical significances were assessed using Student’s T-Test.

^*p < 0.05, stimuli groups compared with control groups (normality).