Table IV.
The recommendation rates for true maximum tolerated dose combinations (MTDCs) and over-dose combinations (ODCs) on average with respect to each type of the dose combination matrix, and position and number of true MTDCs. (The percentages for the best method are in bold).
Rec % for true MTDCs | Rec % for ODCs | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Dose combination matrix | Position and number of true MTDCs | Scenario | YYC | CDP | BW | WCO | HHM | YYC | CDP | BW | WCO | HHM |
Square (i.e., 3 × 3 and 4 × 4) | Diagonal and ⩾2 true MTDCs | 1, 2, 5 | 58 | 74 | 58 | 69 | 58 | 24 | 17 | 23 | 20 | 16 |
Non-diagonal and ⩾2 true MTDCs | 6, 7 | 39 | 45 | 33 | 38 | 40 | 37 | 38 | 33 | 33 | 22 | |
1 true MTDC | 3, 4, 8 | 12 | 26 | 28 | 28 | 32 | 60 | 37 | 42 | 48 | 39 | |
Rectangle (i.e., 2 × 4 and 3 × 5) | Diagonal and ⩾2 true MTDCs | 9, 13 | 35 | 52 | 39 | 44 | 39 | 25 | 28 | 27 | 19 | 14 |
Non-diagonal and ⩾2 true MTDCs | 10, 14, 15 | 35 | 39 | 38 | 44 | 44 | 44 | 20 | 40 | 32 | 25 | |
1 true MTDC | 12, 16 | 2 | 25 | 30 | 31 | 21 | 51 | 32 | 34 | 35 | 31 | |
Avg allocation to true MTDCs (#) | Accuracy index | |||||||||||
Square (i.e., 3 × 3 and 4 × 4) | Diagonal and ⩾2 true MTDCs | 1, 2, 5 | 11 | 16 | 13 | 15 | 11 | 0.57 | 0.72 | 0.54 | 0.65 | 0.54 |
Non-diagonal and ⩾2 true MTDCs | 6, 7 | 10 | 7 | 7 | 8 | 5 | 0.36 | 0.62 | 0.49 | 0.53 | 0.54 | |
1 true MTDC | 3, 4, 8 | 2 | 7 | 7 | 6 | 6 | 0.45 | 0.54 | 0.48 | 0.56 | 0.59 | |
Rectangle (i.e., 2 × 4 and 3 × 5) | Diagonal and ⩾2 true MTDCs | 9, 13 | 6 | 9 | 9 | 10 | 7 | 0.46 | 0.60 | 0.46 | 0.58 | 0.51 |
Non-diagonal and ⩾2 true MTDCs | 10, 14, 15 | 7 | 13 | 7 | 10 | 8 | 0.51 | 0.64 | 0.44 | 0.58 | 0.52 | |
1 true MTDC | 12, 16 | 1 | 10 | 5 | 7 | 4 | 0.35 | 0.59 | 0.51 | 0.58 | 0.48 |