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. Author manuscript; available in PMC: 2016 Mar 24.
Published in final edited form as: Cell Tissue Res. 2012 Aug 3;350(2):199–213. doi: 10.1007/s00441-012-1468-7

Fig. 3.

Fig. 3

ICC within the small intestine. (a) is a cryostat section cut parallel to the circular layer. ICC-IM and ICC-DMP ran parallel to the long axis of smooth muscle fibers within the circular layer (cm, solid arrows). ICC-MY (arrowheads) can be observed within the intermuscular plane between the circular and longitudinal muscle layers (lm) at the level of the myenteric plexus (mg) at higher power. Occasional mast cells (*) were observed along the serosal aspect of the lm and within the cm. (b,c) confocal reconstructions of whole mounts through the jejunum at different magnifications. A dense anastomosing network of ICC-MY was observed at the level of the myenteric plexus that formed connections with adjacent ICC-MY (arrowheads). ICC-IM were also observed along the inner aspect of the circular layer (closed arrows) and occasionally in the longitudinal layer (open arrows). (d) is a digital reconstruction of ICC-IM through the circular layer. ICC-DMP were observed on the inner aspect of the circular layer (arrows) and ICC-IM were observed within the circular layer. ICC-DMP and ICC-IM possessed lateral projections that formed a loose interconnecting network with other ICC-IM (#;d). Scale bars = 50 μm in (d & b) and 25 μm in (c & d)