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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: Nat Chem. 2016 Mar 7;8(4):338–346. doi: 10.1038/nchem.2463

Figure 3. Chemo-enzymatic synthesis of modules.

Figure 3

a–c, Representative chemo-enzymatic approach to the synthesis of linear (a), symmetric (b) and asymmetrically branched (c) modules essential for N-glycan assembly. Reagents and conditions: (i), UDP-galactose, β-1,4-GalT; (ii), GDP-fucose, α-1,3-FucT;(iii), CMP-Neu5Ac, α-2,6-SiaT; (iv), CMP-Neu5Ac, α-2,3-SiaT; (v), GDP-fucose, α-1,2-FucT; (vi), NaOH.