Table 3.
Correlation and regression coefficients
| Variable | Birth weight | Fasting glucose | FFA clamp | Standardized coefficient (β) |
|---|---|---|---|---|
| Basal | ||||
| Glucose (mg/dL) | 0.47 (0.001) | 0.71 (0.001) | ||
| EGP (μmol/min/kg BW/μU/mL) | −0.43 (0.001) | −0.44 (0.001) | −0.42 (0.001) | −0.355 |
| Hyperinsulinemia* | ||||
| IC50 (μU/mL) | 0.33 (0.02) | 0.28 (0.04) | 0.56 (0.001) | |
| ΔGluRd/INS (μmol/min/kg BW/μU/mL) | −0.47 (0.001) | −0.26 (0.06) | −0.35 (0.001) | |
| FFA (mEq/L) | 0.50 (0.001) | 0.71 (0.001) | 0.353 | |
| Model** | R | R2 | Adjusted R2 | Standard error |
| Baseline EGP/INS, FFA clamp | 0.597 | 0.357 | 0.332 | 457.9 |
Data are r (P value), unless otherwise stated. BW, body weight; glucose, maternal fasting plasma glucose concentration; ΔGluRd/INS, change in glucose rate of disappearance per unit change in plasma insulin.
*n under hyperinsulinemic conditions: Lean (n = 9), OB (n = 24), and OB+DM (n = 23).
**Backward regression model including variables identified as best predictors from univariate analyses. Initial variable included above, final variables shown with regression coefficients.