Table 1. Positions and effects of the five temperature sensitivity-associated QTLs identified in cross 3D1 × 3D7.

Trait	Chromosome	LOD score at peak	P-value	Mean 3D1 allele (growth rate/temperature sensitivity)	Mean 3D7 allele (growth rate/temperature sensitivity)	Mean difference	Allele effecta	Percentage of variance explained by QTL (%)	Bayes confidence interval length (kb)	Heat-shock protein candidate genes (gene ID)b
Growth rate (15 °C)	2	4.89	0.001	0.301	0.347	0.046	3D7	9.2	996	68169, 90664
Growth rate (22 °C)	3	4.97	0.002	0.384	0.438	0.054	3D7	9.2	326	—
Growth rate (15 °C)	7	3.95	0.008	0.304	0.345	0.041	3D7	7.5	262	—
Temperature sensitivity	10	11.8	<0.001	1.416	1.199	0.217	3D1	16.6	20	—
Growth rate (22 °C)	11	10.38	<0.001	0.452	0.376	0.076	3D1	17.9	157	111223

Abbreviations: LOD, logarithm of odds; QTL, quantitative trait locus.

^a3D1 indicates that the 3D1 parent allele provided a higher phenotypic mean than the 3D7 parent allele. 3D7 indicates that the 3D7 parent allele provided a higher phenotypic mean than the 3D1 parent allele.

^bData refer to within the 95% Bayes confidence interval.