Table 1. Clinical and laboratory characteristics of 16 children who died from measles-associated pneumonia in a pediatric intensive care unit, National Hospital of Pediatrics, Hanoi, Vietnam, February–June 2014*.
| Pt. no. |
Age, mo/sex |
Days from onset to |
CD4/μL (CD4 %) |
MEAS IgM† |
Laboratory test results (type of test) |
||||
|---|---|---|---|---|---|---|---|---|---|
| PICU admission |
Death |
NPA/TLA (culture) |
Blood (rPCR) |
AdV
TLA (PCR) |
CMV/mL blood (rPCR) |
||||
| 1 | 6/M | 5 | 6 | 530 (28) | + | – | – | ND | ND |
| 2 | 8/M | 4 | 6 | 538 (19) | + | – | – | – | 1.90 × 105 |
| 3 | 14/F | 9 | 12 | 754 (15) | + | – | – | ND | ND |
| 4 | 12/M | 6 | 14 | 714 (31) | + | – | – | + | ND |
| 5 | 8/F | 15 | 17 | 341 (37) | + | – | ND | + | – |
| 6 | 16/F | 16 | 18 | 120 (34) | – | – | – | + | – |
| 7 | 10/M | 22 | 27 | 793 (47) | + | Acinetobacter spp. | Acinetobacter spp. | + | 6.72 × 104 |
| 8 | 8/M | 28 | 30 | 1,084 (26) | + | – | – | ND | ND |
| 9 | 15/M | 10 | 14 | 2,578 (52) | + | – | Candida tropicalis, C. parapsilosis | + | 1.10 × 104 |
| 10 | 4/M | 10 | 15 | 947 (46) | + | – | Klebsiella pneumoniae, K. oxytoca, Enterobacter cloacae, E. aerogenes | + | – |
| 11 | 9/F | 16 | 20 | 372 (29) | + | – | C. albicans | + | 1.10 × 104 |
| 12 | 7/F | 11 | 27 | 472 (21) | – | – | Pseudomonas aeruginosa, Enterococcus faecalis, Stenotrophomonas maltophilia | – | – |
| 13 | 5/F | 5 | 21 | 202 (22) | + | – | – | – | 2.03 × 104 |
| 14 | 4/M | 5 | 24 | 326 (12) | + | – | – | ND | 4.79 × 105 |
| 15 | 7/M | 8 | 25 | 1,732 (49) | + | K. pneumoniae | Staphylococcus haemolyticus | + | 3.20 × 103 |
| 16 | 15/F | 5 | 10 | ND | + | Staphylococcus aureus | – | ND | ND |
*+, positive; –, negative; AdV, adenovirus; CMV, cytomegalovirus; MEAS, measles virus, ND, not done; NPA, nasopharyngeal aspirate; Pt, patient; PICU, pediatric intensive care unit; rPCR, real-time PCR; TLA, trachea lavage aspirate. †Specimens from patients 6 and 12 were positive for measles virus RNA.