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. 2016 Mar 24;11(3):e0152017. doi: 10.1371/journal.pone.0152017

Fig 1. Selective cytotoxicity of AQHAR in human cancer cells.

Fig 1

(A) Cell viability of human cancer and normal cells treated with indicated doses of AQHAR. Human osteosarcoma (U2OS) cells showed dose-dependent decrease in viability; normal fibroblasts (TIG-3) were not affected by the equivalent doses (B) Phase contrast images of human cancer and normal cells showing toxicity of AQHAR (50 μg/ml) to cancer cells only. (C and D) Dose dependent reduction in colony forming efficacy of AQHAR-treated U2OS cells. Results are represented as mean ± SD of three independent experiments. ***p<0.001 denotes statistically significance difference between the control and treated groups. AQHAR, aqueous extract of Helicteres angustifolia L. root.