Table 3. Changes in functional capacity evaluated by cardiopulmonary exercise test (CPET) in patients in each group at baseline and at the end of the study (12 weeks).
Exercise group | Relaxation group | |||
---|---|---|---|---|
Baseline (n = 14) | 12 weeks (n = 14) | Baseline (n = 8) | 12 weeksa (n = 5) | |
Total effort time (min) | 8.5±0.6 | 10.5±0.6d | 9.3±1.0 | 11.0±1.3 |
VATb time (min) | 6.6±0.5 | 8.1±0.3e | 5.1±1.2 | 7.5±1.7 |
Maximal heart rate (bpm) | 129.1±5.0 | 137.9±3.5f | 123.3±7.0 | 110.2±6.5 |
VO2peakc/kg weight (ml/kg/min) | 21.4±0.8 | 23.0±1.3 | 23.5±2.9 | 25.0±3.2 |
Functional limitation evaluated by VO2peak | 10/14 (71.4%) | 6/14 (42.8%) | 5/8 (62.5%) | 3/5 (60%) |
aOnly 5 patients were evaluated by CPET at 12 weeks.
bVAT: ventilatory anaerobic threshold.
cVO2peak: peak oxygen uptake.
dp<0.001
ep = 0.009 vs baseline in the exercise group.
fp = 0.01 vs baseline in the exercise group, and p = 0.001 vs 12 weeks in the relaxation group.
No other statistically significant differences were observed between groups at baseline or at 12 weeks, or between time points in each group.