Table 6. Characteristics of the 226 toxigenic C. difficile strains: genotype and antimicrobial susceptibility.
No.of isolates (%)(total n = 226) | ST | Vancomycin (% R) | Metronidazole (% R) | Fidaxomicin (%R) | Rifaximin (% R) | Levofloxacin (% R) | Ciprofloxacin (% R) | Meropenem (%R) | Chloramphenicol (% R) |
---|---|---|---|---|---|---|---|---|---|
66 (29.2) | 54a | 0 | 0 | 0 | 0 | 39 | 100 | 0 | 3 |
58 (25.6) | 3 | 0 | 0 | 0 | 0 | 24 | 100 | 3.4 | 2 |
24 (10.6) | 35 | 0 | 0 | 0 | 0 | 50 | 100 | 0 | 17 |
22 (9.7) | 2 | 0 | 0 | 0 | 0 | 32 | 100 | 4.5 | 5 |
19 (8.4) | 37 | 0 | 0 | 0 | 0 | 84b | 100 | 0 | 5 |
6 (2.7) | 26 | 0 | 0 | 0 | 0 | 1/6 | 0 | 0 | 0 |
4 (1.8) | 8 | 0 | 0 | 0 | 0 | 0 | 4/4 | 0 | 0 |
4 (1.8) | 48 | 0 | 0 | 0 | 0 | 2/4 | 4/4 | 0 | 0 |
3 (1.3) | 139 | 0 | 0 | 0 | 0 | 3/3 | 3/3 | 0 | 0 |
2 (0.9) | 205 | 0 | 0 | 0 | 0 | 2/2 | 2/2 | 0 | 0 |
2 (0.9) | 99 | 0 | 0 | 0 | 0 | 0 | 2/2 | 0 | 0 |
1 (0.4) | 5 | 0 | 0 | 0 | 0 | 0 | 1/1 | 0 | 0 |
1 (0.4) | 15 | 0 | 0 | 0 | 0 | 1/1 | 1/1 | 0 | 0 |
1 (0.4) | 33 | 0 | 0 | 0 | 0 | 0 | 1/1 | 0 | 0 |
1 (0.4) | 39 | 0 | 0 | 0 | 0 | 1/1 | 1/1 | 0 | 0 |
1 (0.4) | 42 | 0 | 0 | 0 | 0 | 1/1 | 1/1 | 0 | 0 |
1 (0.4) | 51 | 0 | 0 | 0 | 0 | 1/1 | 1/1 | 0 | 0 |
1 (0.4) | 55 | 0 | 0 | 0 | 0 | 0 | 1/1 | 0 | 0 |
1 (0.4) | 69 | 0 | 0 | 0 | 0 | 1/1 | 1/1 | 0 | 0 |
1 (0.4) | 76 | 0 | 0 | 0 | 0 | 0 | 1/1 | 1/1 | 0 |
1 (0.4) | 81 | 0 | 0 | 0 | 0 | 1/1 | 1/1 | 0 | 0 |
1 (0.4) | 129 | 0 | 0 | 0 | 0 | 0 | 1/1 | 0 | 0 |
1 (0.4) | 150 | 0 | 0 | 0 | 0 | 1/1 | 1/1 | 0 | 0 |
1 (0.4) | 234 | 0 | 0 | 0 | 0 | 1/1 | 1/1 | 0 | 0 |
1 (0.4) | 286 | 0 | 0 | 0 | 0 | 0 | 1/1 | 0 | 0 |
1 (0.4) | 289 | 0 | 0 | 0 | 0 | 0 | 1/1 | 0 | 0 |
1 (0.4) | 290 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
a For ST54, ST3, ST35, ST2, and ST37, resistance is expressed as a %; for the remaining STs, the number of resistant isolates is shown.
b Resistance among the different STs was compared using Fisher’s exact test (vs. levofloxacin, P < 0.05)