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. 2016 Mar 24;12(3):e1005872. doi: 10.1371/journal.pgen.1005872

Fig 5. Loss of BRC-1/BRD-1 rescues the progeny lethality of smc-5; him-6 double mutants and suppresses the chromatin bridge formation.

Fig 5

A. Mutation of brc-1 or brd-1 rescues the lethality of smc-5(ok2421); him-6(ok412) double mutants. The progeny viability (%) data are represented as averages of three independent experiments and error bars represent standard deviation. The sample size (n) indicates the number of embryos examined for each genotype. Asterisks indicate statistical significance as determined by two-tailed Student T-test. P Values below 0.05 were consider significant, where p < 0.05 was indicated with *, p < 0.01 with ** and p < 0.005 with ***. B. Representative images of chromosomes in -1 oocytes at diakinesis stained with DAPI and an antibody recognizing the chromosome axis component HIM-3. Scale bars: 2 μm.