Table 3. Regional volume of distribution (VT) estimated using image-derived arterial input function.
MC | CER | BS | CW | TW | MCRSF | CERRSF | BSRSF | CWRSF | TWRSF | |
---|---|---|---|---|---|---|---|---|---|---|
Noncarrier | 2.79±1.00 | 2.75±0.98 | 3.66±1.27 | 3.71±1.49 | 3.35±1.26 | 3.16±1.14 | 2.83±1.02 | 4.20±1.45 | 4.13±1.81 | 3.90±1.56 |
Carrier | 3.70±1.07 | 2.71±0.62 | 3.55±0.80 | 3.68±0.86 | 3.77±0.87 | 5.20±2.06 | 2.80±0.64 | 4.06±0.93 | 3.79±1.01 | 3.72±0.86 |
p | 7.78E-03 | 8.83E-01 | 7.28E-01 | 9.22E-01 | 2.27E-01 | 4.17E-04 | 9.07E-01 | 7.14E-01 | 4.69E-01 | 6.54E-01 |
MC = mean cortical regions; CER = cerebellar cortex; BS = brainstem; CW = core white matter; TW = total white matter; MCRSF = mean cortical regions with RSF partial volume correction; CERRSF = cerebellar cortex with RSF partial volume correction; BSRSF = brainstem with RSF partial volume correction; CWRSF = core white matter with RSF partial volume correction; TWRSF = total white matter with RSF partial volume correction; p is the strength of the group difference, i.e. noncarrier vs. carrier, for each region of interest based on student t-test.