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. 2016 Mar 24;11(3):e0152234. doi: 10.1371/journal.pone.0152234

Fig 4. Repressive histone modifications following GATA-1 overexpression in AML-ELs.

Fig 4

ChIP at the PU.1 gene locus was carried out for the H3K9Me3, H3K27Me3, and H3K9Ac histone tail modifications in OCI-M2 (left) and K562 (right) cells. Grey bars: control cells, dark bars: 48hrs after GATA-1 transgene transfection. Data are relative to control antibody IPs (Y axis). T-test significance: p<0.05 (star). Amplicon positions are shown on the X axis.