. Author manuscript; available in PMC: 2016 Mar 24.

Published in final edited form as: Int J Neuropsychopharmacol. 2011 Apr 28;15(4):509–521. doi: 10.1017/S1461145711000630

Table 2.

Effects of serotonin drugs on Nur77 expression in extra-striatal areas

	Veh	DOI	8-OH-DPAT	MDL11939	Hal	DOI+Hal	8-OH-DPAT+Hal	MDL11939+Hal
Nur77 mRNA levels (% of vehicle)
mPFC	100±12	133±14	125±11	149±11	148±12	122±19	115±7	143±15
CC	100±7	133±8	100±12	143±11^*	116±7	100±11	140±13	135±6
NAcS	100±12	275±36^*	233±32	153±18	338±21^**	434±39^***	562±75^***^##	442±38^***
NAcC	100±14	218±26^*	149±39	209±31	267±42^**	347±27^***	305±31^***	323±23^***
SNc	100±58	264±103	201±129	63±36	2146±342^***	1777±235^***	1996±303^***	1726±337^***
VTA	100±40	144±43	93±17	111±31	1418±155^***	1186±180^***	1024±37^***	848±115^***^##

CC, Cingulate cortex ; Hal, haloperidol; mPFC, medial prefrontal cortex ; NAcC, nucleus accumbens core ; NAcS, nucleus accumbens shell ; SNc, substantia nigra pars compacta ; VTA, ventral tegmental area ; Veh, vehicle.

Values represent mean±S.E.M. from five animals per group

p<0.05,

^**

p<0.01,

^***

p<0.001 vs. Veh group;

^##

p<0.01 vs. haloperidol group.