. Author manuscript; available in PMC: 2016 Mar 24.

Published in final edited form as: Int J Neuropsychopharmacol. 2011 Apr 28;15(4):509–521. doi: 10.1017/S1461145711000630

Table 3.

Effects of serotonin drugs on Nor-1 expression in extra-striatal areas

	Veh	DOI	8-OH-DPAT	MDL11939	Hal	DOI+Hal	8-OH-DPAT+Hal	MDL11939+Hal
Nor-1 mRNA levels (% of vehicle)
mPFC	100±10	35±3^*	71±18	194±27^*	241±38^*	236±50^*	115±16^#	68±20^##
CC	100±15	34±9^*	58±15	220±45^*	228±34^*	211±56^*	119±20^#	41±9^##
NAcS	100±9	46±16	180±58	257±58	589±60^**	526±131^**	773±80^***	101±19^###
NAcC	100±8	80±25	124±40	314±76^*	654±94^***	642±148^**	407±66^**	108±22^###
SNc	100±18	118±46	47±7	42±17	975±162^***	682±88^**	889±135^***	743±125^***
VTA	100±36	159±47	103±19	123±34	1608±188^***	1307±199^***	1128±41^***^#	911±114^***^##

CC, Cingulate cortex ; Hal, haloperidol; mPFC, medial prefrontal cortex ; NAcC, nucleus accumbens core ; NAcS, nucleus accumbens shell ; SNc, substantia nigra pars compacta ; VTA, ventral tegmental area ; Veh, vehicle.

Values represent mean±S.E.M. from five animals per group

p<0.05,

^**

p<0.01,

^***

p<0.001 vs. Veh group;

p<0.05,

^##

p<0.01,

^###

p<0.001 vs. haloperidol group.