Table 2. Changes in clinical and laboratory parameters before and after achieving a sustained viral response. Data are presented as a median with interquartile range in parenthesis for continuous variables.
| Parameter | Before | After | Within patient difference | P-value |
| Clinical | ||||
| BMI (kg/m2) | 26.8 (23.685, 29.777) | 27.58 (23.94, 31.003) | 0.46 (−0.153, 1.588) | 0.012 |
| Laboratory | ||||
| Hemoglobin (g/dL) | 12.84 (11.047, 14.803) | 13.435 (11.793, 14.72) | 0.48 (−0.592, 1.462) | 0.111 |
| Platelet Count (x10E3/μL) | 121.335 (77.875, 147.92) | 136.835 (104.082, 159.67) | 11.835 (−5.165, 34.915) | 0.005 |
| SCL (mg/dL) | 1.13 (0.908, 1.355) | 1.115 (0.918, 1.36) | 0.03 (−0.1, 0.15) | 0.412 |
| Albumin (g/dL) | 4.07 (3.73, 4.3) | 4.37 (4.17, 4.508) | 0.215 (0.07, 0.515) | < 0.001 |
| AST (U/L) | 58.83 (40.665, 80.918) | 24.665 (18.67, 30.415) | −27.335 (−54.165, −14.082) | < 0.001 |
| ALT (U/L) | 62.665 (43.668, 88.418) | 21.665 (16, 33.415) | −34.835 (−65.08, −15.668) | < 0.001 |
| Biliburin, total (mg/dL) | 0.95 (0.73, 1.178) | 0.7 (0.53, 0.948) | −0.215 (−0.4, −0.06) | < 0.001 |
| AP (U/L) | 96.5 (73.75, 134.502) | 84.665 (63.75, 117.418) | −14.835 (−28.338, −0.077) | 0.001 |
| GFR (mL/min/1.73 m2) | 65 (53, 80.498) | 62 (48.502, 78.33) | −1.67 (−8.33, 3.25) | 0.099 |
Abbreviations: BMI, body mass index; SCL, creatinine; AST, aspartate aminotransferase; ALT, alanine aminotransferase; AP, alkaline phosphatase; GFR, glomerular filtration rate.