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Effects of MP and MP plus VK2 on osteogenic differentiation of BMSCs. (A-C) The mRNA expressions of Runx2, OC and ALP of BMSCs were detected by qRT-PCR after 3 weeks of incubation of the osteogenic medium with MP and MP plus different concentrations of VK2. Values shown are mean ± SD (n = 3). (*, significant difference versus the MP group, P < 0.05). (D) Alizarin red staining of BMSCs exposed to MP and MP plus 10-6 M VK2.
