Skip to main content
. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Exp Neurol. 2015 Dec 18;277:46–57. doi: 10.1016/j.expneurol.2015.12.008

Figure 2.

Figure 2

Experimental protocols. A. Protocol 1 was used to test optimal ISIs for producing facilitation. Cathodal (−) or anodal (+) tsDCS, represented as either the downward or upward directed trapezoids, was applied during the period of phasic M1 stimulation. B. Protocol 2 was used to test the effect of patterned M1 electrical stimulation (iTBS) and the effect of concurrent tsDCS. C. Protocol 3 was used in awake animals during locomotion to test the affect of iTBS, with and without c-tsDCS, on cortico-muscular coupling (R-square value of LFP-EMG relationship). This protocol is similar to Protocol 2 except that 5 epochs of iTBSs (3000 pulses total) were delivered within 1630 second. D. The timeline of protocol 4, which was used to test the effect of the combined stimulation (iTBS/c-tsDCS) on motor recovery and CST ipsilateral sprouting in the PTX subgroup. Stimulation for this protocol is the same used in Protocol 3.