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UspA2 and UspA2H have the same binding sites for fibrillar collagens (I, II, and III) and network-forming collagens (IV and VI). (A) Inhibition of M. catarrhalis Bc5 adhesion to immobilized collagens I, II, IV, and VI by the soluble collagens indicated in the key. (B) Inhibition of M. catarrhalis BBH18 adhesion to immobilized collagens I, II, IV, and VI by various soluble collagens. In A and B, the indicated collagens were coated to microtiter plates followed by ELISA.
