Table 1.

Summary of the study schedule.

Acclimatisation	Ranking into groups	Administration of NexGard® or Advocate®
Days −14 to −1	Day −2/−1	Days 0, 14, 28 and 56
Mite counts and clinical symptom assessments (including Photographic documentation, Supplementary Material)	Skin Biopsies	Clinical examinations	Body weight determination
Days −2 or −1, 28, 56 and 83 or 84	Days −7 and 34	Days −14, −7, −2 or −1, 14, 28, 56 and 83 or 84	Days −14, −7, −2 or −1, 13, 27, 55 and 83 or 84