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. 2016 Mar 24;23:14. doi: 10.1051/parasite/2016014

Table 2.

Dosage recommendation for NexGard® and Advocate® according to European labels.

Group Sample size Product Active ingredient(s) Dose rate
1 8 dogs Advocate® Imidacloprid 10% w/v and moxidectin 2.5% w/v spot on solution

  • > 1 kg to 4 kg: one 0.4 mL tube/dog;

  • > 4 kg to 10 kg: one 1.0 mL tube/dog;

  • > 10 kg to 25 kg: one 2.5 mL tube/dog;

  • > 25 kg up to 40 kg: one 4.0 mL tube/dog
2 8 dogs NexGard® Afoxolaner (2.27% w/w)

  • 2 kg to 4 kg: 11 mg afoxolaner;

  • > 4 kg to 10 kg: 28 mg afoxolaner;

  • > 10 kg to 25 kg: 68 mg afoxolaner;

  • > 25 kg to 50 kg: 136 mg afoxolaner.