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. 2016 Mar 3;12(5):545–557. doi: 10.7150/ijbs.13540

Figure 8.

Figure 8

OTUB1-isoform 2 promoted xenograft growth and metastasis in nude mice models. A. A statistical analytical graph of the xenograft tumor growth speed. The error bars are shown. *: p<0.01. B. Representative xenograft images of the Lenti-NC and Lenti-OTUB1-isoform 2 AGS groups. C. A statistical analytical graph of the xenograft tumor weights and volumes. The error bars are shown. *: p<0.01. D. The representative CT-scanning results of Lenti-NC and Lenti-OTUB1-isoform 2 AGS groups. Left: The CT scanning of lung tissues from Lenti-NC and Lenti-OTUB1-isoform 2 AGS groups. Right: The CT scanning of dead mice from Lenti-NC and Lenti-OTUB1-isoform 2 AGS groups. Arrows pointed out the suspicious lesions in lungs under CT-scanning. E. The representative gross photos of lung tissues from Lenti-NC and Lenti-OTUB1-isoform 2 AGS groups. F. The representative H&E photos of lung tissues from Lenti-NC and Lenti-OTUB1-isoform 2 AGS groups. Top: The scale bars=200µm. Bottom: The scale bars=50µm.