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Effect of IL-13Rα1 deficiency on Hb1 and Hb2 infection-induced changes in smooth muscle morphology and function. (A) Concentration-dependent response to acetylcholine (Ach). (B) Frequency-dependent nerve stimulation (EFS). (C) Smooth muscle spontaneous contractions. (D) Contractile responses to 5-HT (10 μM). (E) Smooth muscle thickness. (F) IGF-1 mRNA expression. *, P < 0.05, compared to WT VEH; ϕ, P < 0.05, compared to WT Hb2 infection. n = 5 to 7 per group.
