FIG 6.

Survival and bacterial loads after treatment with resolvins. (A) Survival on days 0 to 17 after S. aureus inoculation after 8 weeks on HFD-S. On days 1 to 4, mice received the vehicle (0.5% ethanol in saline), RvD1, or RvD2. The log rank test was used to determine statistically significant differences (n = 20 mice per group). (B) Bacterial loads in the kidneys on day 6 after S. aureus inoculation after 8 weeks on HFD-S. Two-way ANOVA with the experiment as a nuisance factor was used to determine statistically significant differences (n = 23, 28, and 22 mice per group, respectively). The data shown are the estimated marginal mean plus SEM. *, P < 0.05. Experimental groups: vehicle, RvD1, and RvD2.