FIG 4.

Expression pattern of virulence-related genes involved in the Vibrio cholerae pathogenic cycle. (A) KEGG pathway diagram of virulence-related genes in the Vibrio cholerae pathogenic cycle (generated using the KEGG PATHWAY database [Kanehisa Laboratories]). Genes highlighted in gray are upregulated in JZ6 at 10°C. cAMP, cyclic AMP; MSHA, mannose-sensitive hemagglutinin; TCP, toxin-coregulated pilin. (B) Detection of relative expression levels of six upregulated genes of the Vibrio cholerae pathogenic cycle by qRT-PCR.