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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Am J Geriatr Psychiatry. 2016 Jan 29;24(3):248–258. doi: 10.1016/j.jagp.2015.12.002

Table 2.

Averaged Objective Sleep Measures and Odds of Dementia or MCI

Outcome = MCI or Dementia vs. Normal
Minimally Adjusteda Multivariate Adjustedb

Predictor (average over all nights) OR (95% CI) Wald χ2 [1, N=1245], p-value OR (95% CI) Wald χ2 [1, N=1223], p-value
Total Sleep Time, hours
    Q1 (<6 hrs, 7 min) 0.92 (0.69-1.24) 0.30, p = 0.59 0.85 (0.63-1.16) 1.02, p = 0.31
    Q2-3 (6 hrs to <7.5 hrs) 1.00 (reference) - - 1.00 (reference) - -
    Q4 (≥7.5 hrs) 1.00 (0.75-1.33) 0.00, p = 0.98 0.93 (0.69-1.25) 0.26, p = 0.61
Sleep Efficiency, %
    Q1 (<74.39) 1.55 (1.10-2.18) 6.28, p = 0.01 1.53 (1.07-2.19) 5.34, p = 0.02
    Q2 (74.39 to <81.84) 1.31 (0.93-1.83) 2.37, p = 0.12 1.33 (0.94-1.89) 2.53, p = 0.11
    Q3 (81.84 to <86.26) 1.34 (0.96-1.88) 2.91, p = 0.09 1.38 (0.97-1.95) 3.25, p = 0.07
    Q4 (≥86.26) 1.00 (reference) - - 1.00 (reference) - -
    p-trend 5.40, p = 0.02 4.54, p = 0.03
Wake After Sleep Onset, minutes
    Q1 (<39.25) 1.00 (reference) - - 1.00 (reference) - -
    Q2 (39.25 to <58.33) 1.21 (0.87-1.70) 1.30, p = 0.26 1.27 (0.90-1.80) 1.87, p = 0.17
    Q3 (58.33 to <85.75) 1.16 (0.83-1.62) 0.75, p = 0.39 1.14 (0.80-1.61) 0.51, p = 0.47
    Q4 (≥85.75) 1.21 (0.86-1.69) 1.18, p = 0.28 1.16 (0.81-1.66) 0.66, p = 0.42
    p-trend 0.89, p = 0.35 0.33, p = 0.57
Sleep Latency, minutes
    Q1 (<17.25) 1.00 (reference) - - 1.00 (reference) - -
    Q2 (17.25 to <28.75) 1.08 (0.77-1.52) 0.21, p = 0.65 1.12 (0.79-1.59) 0.41, p = 0.52
    Q3 (28.75 to <47.50) 1.29 (0.92-1.80) 2.16, p = 0.14 1.37 (0.97-1.93) 3.19, p = 0.07
    Q4 (≥47.50) 1.42 (1.01-1.99) 4.14, p = 0.04 1.37 (0.96-1.94) 3.04, p = 0.08
    p-trend 5.06, p = 0.03 4.07, p = 0.04
a

Adjusted for age, race, clinic and education

b

Adjusted for age, race, clinic, education, body mass index, number of depressive symptoms, comorbidities, number of IADL impairments, smoking status, alcohol use, exercise, living alone, self-reported health status, antidepressant use, benzodiazepine use, and prescription sleep medication use.

A separate model was run for each predictor.

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