Table 1.
Characteristic | Premenopausal | Postmenopausal | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
Cases | Controls | P | Cases | Controls | P | |||||
N | Mean (SD) or N (%) | N | Mean (SD) or N (%) | N | Mean (SD) or N (%) | N | Mean (SD) or N (%) | |||
Age | 81 | 45.99 (4.62) | 70 | 45.40 (4.40) | 0.43 | 78 | 56.27 (5.61) | 86 | 56.83 (5.98) | 0.54 |
Race | 81 | 70 | 0.64 | 78 | 86 | 0.07 | ||||
African-American | 17 (20.99) | 16 (22.86) | 17 (21.79) | 30 (34.88) | ||||||
Caucasian | 58 (71.60) | 46 (65.71) | 59 (75.64) | 51 (59.30) | ||||||
Other | 6 (7.41) | 8 (11.43) | 2 (2.56) | 5 (5.81) | ||||||
Menstrual phase | 81 | 70 | 0.91 | NA | ||||||
Follicular | 21 (25.93) | 20 (28.57) | ||||||||
Mid-cycle | 39 (48.15) | 31 (44.29) | ||||||||
Luteal | 21 (25.93) | 19 (27.14) | ||||||||
Menarche age (years) | 81 | 12.68 (1.40) | 70 | 12.58 (1.27) | 0.65 | 78 | 12.65 (1.17) | 86 | 12.18 (1.39) | 0.02 |
Parous | 81 | 66 (81.48) | 70 | 46 (65.71) | 0.04 | 78 | 68 (87.18) | 86 | 68 (79.07) | 0.21 |
Age of first pregnancy (years) | 59 | 27.47 (6.25) | 35 | 27.69 (6.02) | 0.87 | 63 | 25.76 (7.06) | 54 | 26.22 (6.32) | 0.71 |
Pregnancy number | 66 | 2.74 (1.23) | 46 | 2.59 (1.59) | 0.56 | 68 | 2.69 (1.41) | 68 | 2.62 (1.40) | 0.76 |
Ever lactated | 59 | 47 (79.66) | 35 | 29 (82.86) | 0.79 | 63 | 40 (63.49) | 54 | 37 (68.52) | 0.70 |
Duration of lactation (months) | 59 | 12.78 (14.79) | 35 | 13.44 (19.29) | 0.85 | 63 | 9.66 (14.56) | 54 | 14.32 (18.53) | 0.13 |
Years since last birth | 59 | 14.51 (7.03) | 35 | 13.23 (7.79) | 0.42 | 63 | 25.89 (10.60) | 54 | 27.56 (8.93) | 0.36 |
BMI (kg/m2) | 81 | 27.26 (6.30) | 70 | 27.46 (6.55) | 0.85 | 78 | 31.06 (7.16) | 86 | 27.98 (6.13) | <0.01 |
Any previous breast biopsy | 81 | 32 (39.51) | 70 | 6 (8.57) | <0.01 | 78 | 32 (41.03) | 86 | 28 (32.56) | 0.33 |
Positive family history | 46 | 3 (6.52) | 25 | 7 (28.00) | 0.03 | 43 | 10 (23.26) | 35 | 13 (37.14) | 0.22 |
Two of these 317 women were missing menopausal status. The entire population of NAF yielders is 565. Characteristics of the additional 248 NAF yielders are compared to those of 317 women in Online Resource Table S1