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. 2016 Mar 9;146(4):858S–885S. doi: 10.3945/jn.115.220079

TABLE 5.

Recommended zinc biomarkers to assess zinc exposure, status, function, and effect1

Usefulness assessment
Exposure
Status
Function
Effect
Research Clinical Program Research Clinical Program Research Clinical Program Research Clinical Program
Dietary assessment + 0 + + 0 + 0 0 0 0 0 +
Plasma or serum zinc concentration + 0 + + 0 + + 0 + + 0 +
Stunting + 0 0 + 0 0 + 0 + + 0 +
1

0, not useful for the specific purpose; +, useful to some extent and in certain population groups but either not commonly used or important disadvantages (e.g., no reference values); ++, useful in certain population groups, often used with some limitations (e.g., lack of specificity or sensitivity); +++, useful, often used in relevant population groups, with no or only minor limitations. None of the 3 recommended zinc biomarkers met the criteria for ++ or for +++.