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. Author manuscript; available in PMC: 2017 Jan 15.
Published in final edited form as: Adv Drug Deliv Rev. 2015 Dec 4;96:83–102. doi: 10.1016/j.addr.2015.11.020

Fig. 1.

Fig. 1

Quality assessment of engineered tissues. (A) Integration of a combination of structural and functional experimental measurements provides insight into the ability of engineered human stem cell-derived heart tissues to meet design criteria established according to —gold standard measurements made on mature heart tissues. Calculating a composite quality score by averaging the percent differences between the mature and engineered tissue measurement values could allow comprehensive quantitative comparison [108–112]. (B) To build engineered heart constructs, there are several key questions concerning design aspects that we address in this review.