TABLE 1.
Characteristics of participants by MI status1
| MI cases | Non-MI controls | P2 | |
| Participants, n | 1560 | 1751 | — |
| Age, y | 57.7 ± 11.03 | 57.6 ± 11.2 | 0.85 |
| Women, n (%) | 378 (24.2) | 435 (24.8) | 0.68 |
| BMI, kg/m2 | 26.0 ± 3.9 | 26.4 ± 4.3 | 0.0006 |
| Physical activity, total MET-h/d | 34.8 ± 16.0 | 35.6 ± 15.8 | 0.13 |
| Alcohol consumption, g/d | 7.7 ± 20.1 | 6.2 ± 14.8 | 0.01 |
| Total calories, kcal/d | 2744.2 ± 961.9 | 2467.6 ± 773.0 | <0.0001 |
| Current smoker, n (%) | 640 (41.0) | 385 (22.0) | <0.0001 |
| Family history of myocardial infarction, n (%) | 186 (11.9) | 138 (7.9) | 0.0001 |
| Aspirin intake ≥1/wk, n (%) | 314 (20.1) | 269 (15.4) | 0.0004 |
| Individual European admixture proportion, % | 57.5 ± 8.1 | 57.9 ± 7.9 | 0.09 |
| Prevalent diabetes, n (%) | 362 (23.2) | 238 (13.6) | <0.0001 |
| Prevalent hypertension, n (%) | 582 (37.3) | 510 (29.1) | <0.0001 |
| Prevalent hypercholesterolemia, n (%) | 474 (30.4) | 481 (27.5) | 0.06 |
| Household income, $/mo | 510.8 ± 391.5 | 580.3 ± 426.7 | <0.0001 |
| Urban area of residence, n (%) | 600 (38.5) | 708 (40.4) | 0.25 |
| Sugar-sweetened beverages, servings/d | 1.9 ± 1.6 | 1.7 ± 1.3 | 0.01 |
| rs4977574 (risk allele G), n (%) | 0.002 | ||
| AA | 422 (27.1) | 540 (30.8) | |
| AG | 795 (51.0) | 891 (50.9) | |
| GG | 343 (22.0) | 320 (18.3) | |
| rs2383206 (risk allele G), n (%) | 0.02 | ||
| AA | 245 (15.7) | 307 (17.5) | |
| AG | 750 (48.1) | 887 (50.7) | |
| GG | 565 (36.2) | 557 (31.8) | |
| rs1333049 (risk allele C), n (%) | 0.03 | ||
| GG | 338 (21.7) | 435 (24.8) | |
| GC | 821 (52.6) | 922 (52.7) | |
| CC | 401 (25.7) | 394 (22.5) | |
| Genetic risk score, risk allele | 3.2 ± 1.9 | 3.0 ± 1.9 | 0.003 |
1
MET-h, metabolic equivalent task hours; MI, myocardial infarction.
2
For continuous variables, a general linear model was used for comparisons; for categorical variables, the chi-square test was used for comparisons.
3
Mean ± SD (all such values of continuous variables).