TABLE 3.
n | Cases, n | Age adjusted | Multivariable adjusted | Multivariable adjusted plus baseline BMI | |
Total dairy intake, servings/d | |||||
Quintile 1: 0 to <1.0 | 3649 | 1677 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
Quintile 2: 1.0 to <1.5 | 3759 | 1710 | 0.99 (0.93, 1.06) | 1.02 (0.95, 1.09) | 1.03 (0.96, 1.10) |
Quintile 3: 1.5 to <2.1 | 3690 | 1667 | 0.98 (0.92, 1.05) | 1.03 (0.96, 1.10) | 1.05 (0.98, 1.13) |
Quintile 4: 2.1 to <3.1 | 3705 | 1644 | 0.97 (0.91, 1.04) | 1.02 (0.95, 1.10) | 1.01 (0.94, 1.09) |
Quintile 5: ≥3.1 | 3635 | 1540 | 0.91 (0.85, 0.97) | 0.97 (0.90, 1.05) | 0.96 (0.89, 1.04) |
P-trend | — | — | 0.002 | 0.36 | 0.15 |
Low-fat dairy intake, servings/d | |||||
Quintile 1: 0 to <0.3 | 3907 | 1732 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
Quintile 2: 0.3 to <0.7 | 3478 | 1594 | 1.05 (0.98, 1.12) | 1.08 (1.01, 1.16) | 1.08 (1.01, 1.16) |
Quintile 3: 0.7 to <1.1 | 3768 | 1673 | 1.01 (0.94, 1.08) | 1.05 (0.98, 1.13) | 1.07 (1.00, 1.15) |
Quintile 4: 1.1 to <2.0 | 3612 | 1629 | 1.04 (0.98, 1.12) | 1.11 (1.04, 1.19) | 1.09 (1.02, 1.17) |
Quintile 5: ≥2.0 | 3673 | 1610 | 1.02 (0.95, 1.09) | 1.10 (1.02, 1.18) | 1.06 (0.98, 1.13) |
P-trend | — | — | 0.80 | 0.02 | 0.37 |
High-fat dairy intake, servings/d | |||||
Quintile 1: 0 to <0.2 | 4381 | 1979 | 1.00 (reference) | 1.00 (reference) | 1.00 (reference) |
Quintile 2: 0.2 to <0.5 | 3020 | 1408 | 1.00 (0.93, 1.07) | 1.00 (0.93, 1.07) | 0.98 (0.92, 1.05) |
Quintile 3: 0.5 to <0.8 | 3740 | 1679 | 0.94 (0.88, 1.00) | 0.95 (0.89, 1.02) | 0.92 (0.86, 0.99) |
Quintile 4: 1.1 to <1.3 | 3712 | 1624 | 0.90 (0.85, 0.97) | 0.93 (0.87, 0.99) | 0.93 (0.87, 1.00) |
Quintile 5: ≥1.3 | 3585 | 1548 | 0.90 (0.84, 0.96) | 0.92 (0.85, 0.98) | 0.92 (0.86, 0.99) |
P-trend | — | — | 0.0003 | 0.007 | 0.04 |
HRs and 95% CIs were calculated with the use of Cox proportional hazards regression models. Multivariable-adjusted HRs were adjusted for age, randomization treatment, smoking status, physical activity, postmenopausal status, postmenopausal hormone use, history of hypercholesterolemia, history of hypertension, multivitamin use, alcohol intake, energy intake, and fruit and vegetable intake.