Table 1.
Summary of Models for the Active States of the [NiFe]-Hydrogenasea
| state | core description | state of the art models | comment |
|---|---|---|---|
| Ni-R | NiII–H–FeII | [(diphos)Ni(pdt)(μ-H)Fe(CO)2L]+14 [(amine)2Ni(SR)2(μ-H)FeL3]+ 15 |
models: dFe–H < dNi–H enzyme: dFe–H > dNi–H16 |
| Ni-SI | NiII–_–FeII | [(diphos)Ni(SR)2Fe(CO)2L2]+ 17 | model: six-coordinated iron enzyme: five-coordinated iron18 |
| Ni-C | NiIII–H–FeII 19 | none | no progress |
| Ni-L | NiI–_–FeII | [(diphos)Ni(pdt)Fe(CO)2L]+ 20 | model: NiIIFeI vs enzyme: NiIFeII 16 |
a
diphos = R2PCH2CH2PR2; (amine)2(SR)2 = tetradentate diaminodithiolate;15 L = PR3 or P(OR)3; pdt2− = CH2(CH2S−)2.