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. 2016 Mar 25;11(3):e0152176. doi: 10.1371/journal.pone.0152176

Fig 3. Functional deficits and recovery following MCAO.

Fig 3

A: Sham rats exhibited neurological scores that were not significantly altered compared to their pre-surgery baseline score (day 0). B: Following MCAO, rats exhibited a significant reduction in neurological score at 3 days followed by gradual recovery such that at 28 days there was no difference compared to their pre-MCAO baseline scores. C: Sham rats did not exhibit alterations in the removal difference times between the affected versus unaffected forepaws at any timepoint after surgery compared to pre-surgery baseline. D: MCAO resulted in significantly increased removal difference times between the affected and unaffected forepaws at 3 and 7 days and this deficit gradually recovered such that at 28 days there was no difference compared to pre-MCAO baseline measurements. Data analysed by Friedman’s test followed by Dunn’s multiple comparisons test; **p<0.001 versus day 0; ***p<0.0001 versus day 0.