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Illustration of fatty-acid biosynthesis in the P. falciparum apicoplast and a proposed strategy to target ENR with inhibitors. Abbreviations are as follows: acyl carrier protein (ACP), malonyl transferase (MAT), β-ketoacyl acyl carrier protein reductase (KR), 3-hydroxyacyl ACP dehydrase (DH), enoyl-acyl carrier protein reductase (ENR), β–ketoacyl acyl carrier protein synthetase (KS), and coenzyme A (CoA).
