Table 2. The top ten down-regulated genes in highly invasive and metastatic cells (PC-1.0) compared with weakly invasive and metastatic cells (PC-1).

Name	Gene Name	Phosphorylation Site	PC-1	PC-1.0	Ratio
Smad1	SMAD family member 1	Ser187	2.53	0.67	0.26
BID	BH3 interacting domain death agonist	Ser78	1.51	0.46	0.30
ACTC1	Actin, alpha cardiac muscle 1	Tyr55	1.48	0.47	0.32
Smad2	SMAD family member 1	Ser250	2.29	0.74	0.32
GRK1	G protein-coupled receptor kinase 1	Ser21	2.28	0.79	0.35
AKT1	v-akt murine thymoma viral oncogene homolog 1	Ser124	1.29	0.46	0.36
Cytokeratin 8	keratin 8, type II	Ser431	3.83	1.45	0.38
c-Raf	Raf-1 proto-oncogene, serine/threonine kinase	Ser296	1.03	0.40	0.39
Smad2	SMAD family member 2	Thr220	1.55	0.61	0.39
PDGF R alpha	platelet-derived growth factor receptor, alpha polypeptide	Tyr849	1.19	0.49	0.41