Table 2.
Clinical and diagnostic uses of FISH (modified13).
CLINICAL USES OF FISH | |
---|---|
1. | Prenatal testing |
2. | Transplant pathology |
3. | XY FISH on sex-mismatched organ transplant |
4. | Disease relapse using known genetic alterations in primary tumor |
5. | Oncology (diagnostic, prognostic, and/or predictive markers) |
6. | Chromosomal aneusomies |
7. | Gene/Locus deletions |
8. | Gene amplifications |
9. | Translocation |
10. | Congenital abnormalities, such as Trisomy 13, 18, 21, XY aneusomies, Microdeletion syndromes, Cri-du-chat (5p), Prader-Willi/Angelman (15q). |