Table 1.

Demographics and baseline characteristics of all subjects in the hepatic and renal impairment studies

Trial 1222.20	Healthy subjects	Mild hepatic impairment	Moderate hepatic impairment	Trial 1222.35	Healthy subjects	Severe renal impairment
n	16	8	8	n	14	8
Sex, n (%)				Sex, n (%)
Male	12 (75)	6 (75)	6 (75)	Male	11 (78.6)	6 (75.0)
Female	4 (25)	2 (25)	2 (25)	Female	3 (21.4)	2 (25.0)
Age, years				Age, years
Mean	54.1	51.9	56.5	Mean	57.6	59.4
SD	9.6	8.9	9.4	SD	8.9	11.5
Minimum/maximum	36/70	42/70	40/67	Minimum/maximum	39/70	39/73
Height, cm				Height, cm
Mean	174.8	178.1	174.6	Mean	177.4	175.4
SD	9.3	8.3	9.3	SD	7.1	6.7
Minimum/maximum	154/188	164/190	160/183	Minimum/maximum	164/188	167/184
Weight, kg				Weight, kg
Mean	83.4	88.6	84.9	Mean	81.7	77.0
SD	13.9	17.5	18.7	SD	10.3	15.0
Minimum/maximum	54/100	53/105	60/110	Minimum/maximum	71/102	65/110

Abbreviation: SD, standard deviation.