Table 2.

Univariate and multivariate analysis for overall survival (Cox regression analysis)

Parameters	Univariate analysis			Multivariate analysisa
	RR	95% CI	P-value	RR	95% CI	P-value
Age (years)	0.753	0.447–1.268	0.286	–	–	–
Sex	0.925	0.463–1.848	0.826	–	–	–
Histological differentiation	2.310	1.504–3.546	<0.0001*	1.945	1.273–2.972	0.002*
Cirrhosis	1.032	0.663–1.606	0.891	–	–	–
Tumor size	1.932	1.253–2.979	0.003*	1.308	0.806–2.121	0.277
Clinical stage (T stage)	2.435	1.673–3.544	<0.0001*	2.038	1.347–3.084	0.001*
PLCB1 expression	2.096	1.317–3.336	0.002*	1.706	1.039–2.801	0.035*

Notes:

^aFinal multivariate analysis include only those covariates that were significantly associated with survival (P<0.05);

^*P<0.05; – indicates data not available.

Abbreviations: PLCB1, phospholipase C, β1; RR, relative risk; CI, confidence interval.