Table 5. Gender effects on association of FOXO3, AKT1 and IGF-2R with longevity.

		MAF
SNP	Gender	Cases/controls	OR	95%CI	Pa
rs13217795	All	0.31/0.28	1.13	0.94-1.34	0.19
	Men	0.32/0.28	1.22	0.93-1.60	0.15
	Women	0.30/0.28	1.09	0.86-1.37	0.49
rs2764264	All	0.31/0.28	1.13	0.94-1.34	0.19
	Men	0.32/0.28	1.18	0.90-1.55	0.24
	Women	0.30/0.28	1.11	0.88-1.40	0.38
rs3803304	All	0.08/0.10	0.80	0.60-1.06	0.12
	Men	0.08/0.12	0.69	0.45-1.06	0.092
	Women	0.08/0.09	0.91	0.62-1.33	0.63
rs9400239	All	0.32/0.28	1.19	1.00-1.41	0.057
	Men	0.33/0.28	1.26	0.96-1.65	0.095
	Women	0.31/0.27	1.16	0.92-1.47	0.20
rs1935949	All	0.29/0.27	1.12	0.94-1.34	0.22
	Men	0.31/0.27	1.20	0.91-1.59	0.19
	Women	0.28/0.27	1.08	0.86-1.37	0.50
rs9486902	All	0.06/0.04	1.76	1.21-2.57	0.003
	Men	0.07/0.04	1.64	0.95-2.81	0.073
	Women	0.06/0.03	2.03	1.19-3.46	0.008
rs2494731	All	0.35/0.35	1.01	0.86-1.20	0.87
	Men	0.35/0.35	0.99	0.76-1.28	0.91
	Women	0.35/0.34	1.05	0.84-1.30	0.69
rs2494732	All	0.26/0.27	0.94	0.78-1.13	0.50
	Men	0.27/0.29	0.93	0.70-1.22	0.59
	Women	0.25/0.26	0.97	0.76-1.23	0.80
rs2498796	All	0.37/0.38	0.96	0.81-1.13	0.64
	Men	0.37/0.38	0.96	0.75-1.25	0.78
	Women	0.37/0.38	0.96	0.77-1.20	0.73
rs2494738	All	0.46/0.48	0.92	0.78-1.08	0.29
	Men	0.46/0.51	0.84	0.65-1.08	0.17
	Women	0.46/0.46	0.99	0.80-1.22	0.93
rs1130214	All	0.09/0.09	0.98	0.74-1.30	0.88
	Men	0.08/0.09	0.87	0.56-1.37	0.55
	Women	0.09/0.09	1.06	0.73-1.53	0.75
rs9456497	All	0.48/0.49	0.98	0.83-1.15	0.77
	Men	0.46/0.51	1.21	0.94-1.55	0.14
	Women	0.50/0.49	0.94	0.76-1.16	0.59

^aP, P has not been adjust for gender