Table 7. AKT1 haplotype associated with human longevity in a Han Chinese population.
Haplotype* | Frequency | Case, control frequencies | Chi-square | P-value | OR(95% CI) |
---|---|---|---|---|---|
CGCTAG | 0.435 | 0.432,0.437 | 0.066 | 0.80 | |
GGTCGG | 0.201 | 0.224,0.176 | 8.644 | 0.003 | 1.4(1.1-1.7) |
CCCTGG | 0.078 | 0.085,0.070 | 1.981 | 0.16 | |
CGCTGG | 0.056 | 0.049,0.063 | 2.073 | 0.15 | |
GGCCGG | 0.043 | 0.038,0.047 | 1.077 | 0.30 | |
GGTCAG | 0.039 | 0.029,0.051 | 7.754 | 0.005 | 0.56(0.37-0.85) |
GGCCGT | 0.034 | 0.032,0.037 | 0.568 | 0.45 | |
CGCTAT | 0.031 | 0.034,0.028 | 0.629 | 0.43 | |
CGCCGG | 0.022 | 0.020,0.023 | 0.235 | 0.63 | |
GGTCGT | 0.012 | 0.013,0.011 | 0.188 | 0.67 |
The haplotypes were generated from SNPs rs3803304, rs2494731, rs2494732, rs2498796, rs2494738, rs1130214.