Table 1. Summary of clinical and pathologic features.
| Feature | n (%) rpS6 | n (%) p-rpS6 |
|---|---|---|
| Sex | ||
| Male | 351 (61) | 369 (62) |
| Female | 229 (39) | 229 (38) |
| Age at surgery (y) | ||
| < 65 | 352 (60) | 368 (61) |
| >= 65 | 228 (40) | 230 (39) |
| Tumor extent (TNM 2009) | ||
| pT1 | 310 (53) | 317 (53) |
| pT2 | 62 (11) | 71 (12) |
| pT3a | 76 (13) | 73 (12) |
| pT3b | 105 (18) | 106 (18) |
| pT3c | 16 (3) | 20 (3) |
| pT4 | 11 (2) | 11 (2) |
| Regional lymph node metastasis (TNM 2009) | ||
| N0/pN0 | 528 (91) | 549 (92) |
| pN1/pN2 | 52 (9) | 49 (8) |
| Distant metastasis (TNM 2009) | ||
| M1 | 114 (20) | 112 (19) |
| M0 | 466 (80) | 486 (81) |
| Grade of malignancy | ||
| G1 | 137 (24) | 130 (22) |
| G2 | 335 (58) | 356 (60) |
| G3 | 100 (17) | 105 (18) |
| G4 | 2 (0) | 1 (0) |
| Type of surgery | ||
| Radical nephrectomy | 492 (85) | 510 (85) |
| Partial nephrectomy | 88 (15) | 88 (15) |
| Histopathological subtype | ||
| Clear cell (conventional) RCC | 486 (84) | 496 (83) |
| Papillary (chromophil) RCC | 54 (9) | 56 (9) |
| Chromophobe RCC | 23 (4) | 27 (5) |
| Spindle cell carcinoma | 6 (1) | 6 (1) |
| Collecting duct carcinoma | 3 (0) | 2 (0) |
| Unclassified | 8 (1) | 11 (1) |