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. 2015 Nov 22;7(1):490–508. doi: 10.18632/oncotarget.6357

Figure 3. The expression of hIF1 increased DEN-induced hepatocarcinogenesis (HCC).

Figure 3

A.-C. Changes in body weight (A), liver weight (B) and blood GPT (C) in PBS or DEN-treated CRL (open bars) and hIF1 Tet-Off T/H (closed bars) mice, treated in presence (+) or absence (−) of Dox. D. CRL and T/H livers of mice treated (+) or not treated (−) with DEN. The effect of Dox administration (+) or not (−) is also shown. The number of tumors and the total tumor volume in DEN-treated CRL (open bars) and T/H (closed bars) mouse livers treated (+) or not (−) with Dox. The number of mice is indicated in parenthesis. Results are means ± SEM. P values by Student's t test are indicated.